Publications by authors named "Julien Gervais"

Article Synopsis
  • The strength of cellulose comes from how β-1,4-linked glucan chains are arranged in a para-crystalline structure, created during plant cellulose biosynthesis via a complex that synthesizes multiple chains simultaneously.
  • Understanding how cellulose fibrils form and align with cell walls raises questions about the synchronization of polymerization rates among subunits in the synthesis complex.
  • Mathematical modeling and molecular dynamics simulations showed that glucan chains initially form an uncrystallized aggregate, which can then reorganize into a protofibril using bonding interactions, supporting the idea that this process allows flexibility in cellulose alignment.
View Article and Find Full Text PDF

There is a lack of early biomarkers of intervertebral disc (IVD) degeneration. Thus, the authors developed the analysis of magnetic resonance signal intensity distribution (AMRSID) method to analyse the 3D distribution of the T2-weighted MR signal intensity within the IVD using normalised histograms, weighted centres and volume ratios. The objective was to assess the sensitivity of the AMRSID method to the segmentation process and data normalisation.

View Article and Find Full Text PDF

Background: Early stages of scoliosis and spondylolisthesis entail changes in the intervertebral disc (IVD) structure and biochemistry. The current clinical use of MR T2-weighted images is limited to visual inspection. Our hypothesis is that the distribution of the MRI signal intensity within the IVD in T2-weighted images depends on the spinal pathology and on its severity.

View Article and Find Full Text PDF