Functional Validation of a New Alginate-based Hydrogel Scaffold Combined with Mesenchymal Stem Cells in a Rat Hard Palate Cleft Model.

Background: One of the major difficulties in cleft palate repair is the requirement for several surgical procedures and autologous bone grafting to form a bony bridge across the cleft defect. Engineered tissue, composed of a biomaterial scaffold and multipotent stem cells, may be a useful alternative for minimizing the non-negligible risk of donor site morbidity. The present study was designed to confirm the healing and osteogenic properties of a novel alginate-based hydrogel in palate repair.

Intraosseous microdialysis for bone free flap monitoring in head and neck reconstructive surgery: A prospective pilot study.

Background: Although some researchers have positioned microdialysis catheters in the soft tissue surrounding bone, the results did not accurately reflect bone metabolism. The present study's objective was to establish the feasibility of microdialysis with a catheter positioned directly in bone.

Methods: Thirty-four patients (19 males, 15 females; median age: 59) were included in a prospective, nonrandomized clinical trial in the Department of Maxillofacial Surgery at Amiens-Picardie University Hospital (Amiens, France).

Vascular anatomy of the free fibula flap including the lateral head of the soleus muscle applied to maxillo-mandibular reconstruction.

Purpose: Initially described by Baudet in 1982, the fibula flap including the lateral head of the soleus muscle allows a one-stage reconstruction for large maxillo-mandibular defects. The aim of this study was to evaluate the number of muscular branches destined to the soleus muscle and their distance from the origin of the fibular artery, to assess the vascular anatomy of the free fibula flap including the lateral head of the soleus muscle applied to maxillo-mandibular reconstruction.

Methods: We performed a cadaveric anatomic study on ten lower limbs, and a CT angiography anatomic study on 38 legs.

Face graft? Extrapolation of facial allotransplantation to children.

The possibility to imagine a vascularized composite allotransplantation for disfigured children is felt more critical than for adults non on technical point of view but in terms of indications and justifications. The question is not about surgery. It is related to the pathologies themselves for which transplant could be suitable.

Infant Odontogenic Myxoma: a specific entity.

Introduction: In children, and specifically in infants, odontogenic myxomas are extremely rare. In infants, myxoma seems to display mostly the same clinical, radiological and pathological characteristics. This paper presents a series of odontogenic myxomas in infant patients.

Midface osteotomies lines: evolution by Paul Tessier, the second Tessier classification.

The Tessier collection is an inheritance of a whole career of a surgeon and a life dedicated to cranio-facial malformations. It is a good opportunity to analyse some particular points of the surgical work of Paul Tessier, in particular to understand how the midface advancement procedures were made up and thought out. Medical files, pictures, X-rays and drawings help us to describe step by step the different types of midface osteotomies done by Paul Tessier, from TESSIER I to TESSIER VII osteotomies.