Publications by authors named "Julien Claudel"

The possibility of interference by electromagnetic fields in the workplaces with cardiac implants is a concern for both individuals and employers. This article presents an analysis of the interference to which cardiac implants are subjected under high-intensity electric field at the power frequency.Evaluations of interference were conducted by studying the induced voltages at the device input in the real case study and the substitute study, and establishing an association between them with the equivalence factor.

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Previous studies have demonstrated the electropermeabilization of cell membranes exposed to an electric field with moderate intensity (<2 V/cm) and a frequency of <100 MHz. Bioimpedance spectroscopy (BIS) is an electrical characterization technique that can be useful in studying this phenomenon because it is already used for electroporation. In this paper, we report a device designed to perform BIS on single cells and expose them to an electric field simultaneously.

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In light of concerns regarding the occupational safety and health of workers wearing active implantable medical devices (AIMDs), this study aims to investigate the potential risks of electromagnetic interference (EMI) between AIMDs and low-frequency 50/60 Hz electromagnetic fields (EMFs) in the workplace. A total of 58 AIMDs, consisting of pacemakers (PMs) and implantable cardiac defibrillators (ICDs) of different brands, models, and configurations were tested to determine the immunity thresholds for high-voltage electric fields (EFs) and magnetic fields (MFs) at 50/60 Hz. The EFs and MFs at the levels in workplaces are reproduced by setups using Helmholtz coils and aluminum plates, respectively, to ensure that the EM/MF exposures are controllable and reproducible.

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Interdigitated (ITD) sensors are specially adapted for the bioimpedance analysis (BIA) of low-volume (microliter scale) biological samples. Impedance spectroscopy is a fast method involving simple and easy biological sample preparation. The geometry of an ITD sensor makes it easier to deposit a sample at the microscopic scale of the electrodes.

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New technologies, such as biosensors and lab-on-a-chip, are reducing time consumption and costs for the detection and characterization of biological cells. One challenge is to detect and characterize cells and bacteria one by one or at a very low concentration. In this case, measurements have very low variations that can be difficult to detect.

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This paper proposes a simple approach to optimize the operating frequency band of a lab-on-a-chip based on bio-impedance cytometry for a single cell. It mainly concerns applications in low-conductivity media. Bio-impedance allows for the characterization of low cell concentration or single cells by providing an electrical signature.

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The limit of detection of a biological sensor is an important parameter because, when it is optimized, it allows the detection of a reduced number of biological cells and the reduction of the detection time. This parameter can be improved upon with a reduction in electrode size, but the rate of detection is similarly reduced as well. To avoid this problem, we propose a sensor matrix composed of 20 × 20 µm² coplanar square electrodes with a standard clean room manufacturing process.

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