Publications by authors named "Julien Bachour"

Article Synopsis
  • Fox-Fordyce disease (FFD) is a rare chronic inflammation of the apocrine sweat glands, primarily characterized by itchy, raised bumps in areas where these glands are present, such as the underarms and genitals.
  • Research highlights that most affected individuals are young females, with the condition often appearing bilaterally and showing improvement post-menopause.
  • The study suggests that FFD can either be sporadic or familial, may sometimes be asymptomatic, and highlights the need for more clinical trials to explore various treatment options.
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Gabapentin and doxepin are well-known treatments of uremic pruritus in hemodialysis patients but no head-to-head studies were conducted to date. The aim of this trial is to compare the efficacy and the tolerability of gabapentin and doxepin in the treatment of uremic pruritus in hemodialysis patients. A single-blind crossover randomized trial was conducted that included hemodialysis patients with uremic pruritus.

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Importance: Scleromyxedema is a chronic disease with high morbidity and mortality and no definitive therapeutic guidelines.

Objective: To review all available data on the efficacy and the safety of the available treatments of scleromyxedema and suggest a possible therapeutic approach.

Evidence Review: We performed a systematic literature review in Pubmed/Medline, Embase, and Cochrane collaboration databases, searching for all articles since 1990 on the treatments of scleromyxedema, with no limits on participant age, gender, or nationality.

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Stiff skin syndrome is a rare disease causing stony hard induration of skin usually in early childhood. We report a case of 12 years old boy who presented to our clinic with biopsy showing adipocyte entrapment which we believe is an unrecognized key pathological finding in diagnosis of this entity.

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