Meeting Report: Controlled Human Influenza Virus Infection Model Studies: Current Status and Future Directions for Innovation.

On November 13-14, 2023, the National Institute of Allergy and Infectious Diseases (NIAID) in partnership with the Task Force for Global Health, Flu Lab, the Canadian Institutes of Health Research, and the Centers for Disease Control and Prevention convened a meeting on controlled human influenza virus infection model (CHIVIM) studies to review the current research landscape of CHIVIM studies and to generate actionable next steps. Presentations and panel discussions highlighted CHIVIM use cases, regulatory and ethical considerations, innovations, networks and standardization, and the utility of using CHIVIM in vaccine development. This report summarizes the presentations, discussions, key takeaways, and future directions for innovations in CHIVIMs.

Bridging Intention and Action for Employee Well-Being Using the Intentional Action (InAct) Process: Workshop-Lecture Series.

Background: Employee wellness programs can help manage stress and alleviate burnout.

Objective: To pilot and disseminate the Intentional Action(InAct) concept for employee wellbeing.

Methods: Five independent interactive workshop-lectures with an automated audience response system.

Extending the continuum of care poststroke: creating a partnership to provide a community-based wellness program.

Opportunities for individuals poststroke to continue to exercise once formal rehabilitation has ended are limited and in many cases do not exist. Given the incidence of recurrent stroke, and the known and important role exercise plays in reducing stroke risk factors, extending the continuum of care beyond outpatient and home health services to include life-long fitness opportunities for those living with poststroke disability is needed. This article first describes the creation of a partnership between a health care system and a local fitness center to provide an affordable, accessible, safe, community-based exercise program for individuals poststroke and the subsequent development of the flagship program.

New directions in neuroregeneration.

Neurons in the adult mammalian central nervous system (CNS) do not spontaneously regenerate their axons after injury. Despite significant progress in the field of axonal regeneration, effective therapeutic strategies to promote functional recovery after injury are not available. The development of novel therapeutics will require further insights into the intrinsic and extrinsic mechanisms that restrict regeneration in the adult CNS.

Acceptability and satisfaction using Quick Start with the contraceptive vaginal ring versus an oral contraceptive.

Background: Many women discontinue their use of hormonal contraception, and even those who continue so may have difficulty using oral contraceptive pills consistently. New delivery systems, including the vaginal ring, may be easier to use, but user acceptability and satisfaction with these new methods may be affected by women's experience with their bodies.

Materials And Methods: Data for this study were collected as part of a randomized clinical trial on 201 women comparing immediate start of vaginal ring use with immediate start of low-dose oral contraceptive use.

Bleeding patterns after immediate initiation of an oral compared with a vaginal hormonal contraceptive.

Objective: This study compared 84-day bleeding patterns after immediate initiation of a triphasic oral contraceptive with a 25-mug daily dose of ethinyl estradiol (E2) compared with the contraceptive vaginal ring, which has a 15-mug daily dose of ethinyl E2.

Methods: This was an open-label controlled trial. We randomly assigned 201 women to immediate start of a contraceptive pill or immediate start of the ring in a 1:1 allocation ratio.