The impact of an interactive online informational and peer support application (app) for patients with low anterior resection syndrome (LARS) on quality of life: a multicenter randomized controlled trial.

Introduction: Low Anterior Resection Syndrome (LARS) describes bowel dysfunction post-restorative proctectomy (RP) and is associated with poor quality of life (QoL). The aim of this study was to assess the impact of an interactive online informational and peer support App on participants' QoL (primary outcome), LARS, and emotional distress (secondary outcomes).

Methods: A multicentre, randomized, parallel-group trial was conducted across five Canadian colorectal surgery practices.

The use of patient-generated health data in the management of low anterior resection syndrome: a qualitative study.

Background: The cornerstone of low anterior resection syndrome (LARS) treatment is self-management, which requires patient engagement. Colorectal surgeons and nurses may use patient-generated health data (PGHD) to help guide patients in their use of self-management strategies for LARS. However, the perspectives of LARS experts on the use of PGHD remain largely unexplored.

Planetary Health in Nursing: A Scoping Review.

Aim: To map the extent of the use of the term 'planetary health' in peer-reviewed nursing literature.

Design: Scoping Review.

Data Sources: CINAHL, ProQuest Nursing & Allied Health Premium, MEDLINE, APA PsycINFO, ProQuest Dissertations & Theses and Web of Science were searched in January and February 2024 for English and French-language publications.

Young peoples' experience of living with ulcerative colitis and an ostomy.

Inflammatory bowel disease is a significant illness among young people, requiring some of them to get an ostomy; however, there is minimal research that seeks to understand the meanings young people assign to their inflammatory bowel disease experiences. The purpose of this phenomenological study was to arrive at an understanding of the lived experiences of young persons with inflammatory bowel disease and an ostomy. Six young adults (19-24 years of age) diagnosed with ulcerative colitis, and who all had had an operation for a temporary ostomy, participated in individual open-ended interviews.

The use of a nursing model to understand diarrhea and the role of probiotics in patients with inflammatory bowel disease.

Inflammatory bowel disease, an umbrella term used for Crohn disease and ulcerative colitis, is often accompanied with the presenting symptom of diarrhea. This symptom can be a great nuisance and emotionally distressing to the individual with inflammatory bowel disease. Although the exact etiology of inflammatory bowel disease is still unknown, interactions between the host susceptibility, mucosal immunity, and intestinal microflora are thought to be major factors.

Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin.

Drosophila Enhancer of Polycomb, E(Pc), is a suppressor of position-effect variegation and an enhancer of both Polycomb and trithorax mutations. A homologous yeast protein, Epl1, is a subunit of the NuA4 histone acetyltransferase complex. Epl1 depletion causes cells to accumulate in G2/M and global loss of acetylated histones H4 and H2A.