Publications by authors named "Julie Roque"

Article Synopsis
  • PDAC (pancreatic ductal adenocarcinoma) is a highly aggressive cancer with a complex structure that makes it difficult to treat with standard chemotherapy.
  • The study focused on different immune checkpoint proteins in the blood of 32 PDAC patients and found strong connections between their levels and patient survival rates.
  • The researchers established specific plasma level thresholds for these immune markers that can indicate shorter survival, which were validated in a separate group of 27 patients, suggesting that monitoring these levels could improve treatment strategies for PDAC.
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The antioxidant activity of resveratrol (1) and several acylated and glycosylated derivatives on fish oil enriched systems has been studied. Two long-chain acylated derivatives, 3-stearoylresveratrol (2) and 4'-stearoylresveratrol (3), and three glucosyl derivatives, resveratrol-3-beta-d-glucopyranoside (piceid, 4), resveratrol-3,5-di-beta-d-glucopyranoside (5), and resveratrol-3,4'-di-beta-d-glucopyranoside (6), have been prepared and tested. The results have shown a notable antioxidant capacity of resveratrol and piceid in fish oil-in-water emulsions, similar to that of the potent antioxidant hydroxytyrosol.

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