Defining sepsis in small animals.

Objective: To discuss the definitions of sepsis in human and veterinary medicine.

Design: International, multicenter position statement on the need for consensus definitions of sepsis in veterinary medicine.

Setting: Veterinary private practice and university teaching hospitals.

Serial analysis of blood biomarker concentrations in dogs with pneumonia, septic peritonitis, and pyometra.

Background: Prolonged antimicrobial drug (AMD) treatment is associated with antimicrobial resistance development. Biomarker measurement may aid treatment decision-making.

Objectives: Investigate temporal changes in blood biomarker concentrations in dogs undergoing treatment for pulmonary and intra-abdominal infections; compare time to biomarker concentration normalization with duration of clinician-directed AMD treatment.

Patterns of antimicrobial drug use in veterinary primary care and specialty practice: A 6-year multi-institution study.

Background: Combatting antimicrobial resistance requires a One Health approach to antimicrobial stewardship including antimicrobial drug (AMD) use evaluation. Current veterinary AMD prescribing data are limited.

Objectives: To quantify companion animal AMD prescribing in primary care and specialty practice across 3 academic veterinary hospitals with particular focus on third-generation cephalosporins, fluoroquinolones, and carbapenems.