Publications by authors named "Julie Gratieux"

Article Synopsis
  • Spontaneous occlusion of brain arteriovenous malformations (bAVMs) is rare, especially in unruptured cases, with factors like single-venous drainage and small nidus size potentially contributing.
  • A case study describes an unruptured left-sided bAVM in a middle-aged male with a long history of refractory epilepsy, highlighting its spontaneous thrombosis without any signs of bleeding.
  • The report underscores the distinction between occlusion caused by rupture and true spontaneous thrombosis in bAVMs.
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Objective: To assess whether RAF and MEK inhibitors (RAFi/MEKi) can provide long-term clinical benefit in adult patients with V600-mutant glial and glioneuronal tumors (GGNTs), we analyzed tumor response and long-term outcome in a retrospective cohort.

Methods: We performed a retrospective search in the institutional databases of 6 neuro-oncology departments for adult patients with recurrent or disseminated V600-mutant GGNTs treated with RAFi/MEKi.

Results: Twenty-eight adults with recurrent or disseminated V600-mutant gangliogliomas (n = 9), pleomorphic xanthoastrocytomas (n = 9), and diffuse gliomas (n = 10) were included in the study.

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Objective: Few classifications of intradural spinal arteriovenous shunts (ID-SAVSs) have considered their anatomical localization in relation to their phenotype and angioarchitectonics. The authors propose another vision of ID-SAVSs allowing a reappraised classification based on analysis of the anatomical disposition, angioarchitecture, and histogenetic location of these vascular malformations.

Methods: The radiological and clinical records of 210 patients with ID-SAVSs were retrospectively reviewed, considering their localization, vascular architectonics, and correlation with the 5 histogenetic units of the spinal cord.

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