What is the impact of local control in Ewing sarcoma: analysis of the first Brazilian collaborative study group - EWING1.

Background: Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control modality (surgery, surgery plus radiotherapy, and radiotherapy) on clinical outcomes such as survival and recurrence in patients with non-metastatic Ewing sarcoma treated on the first Brazilian Collaborative Group Trial of the Ewing Family of Tumors (EWING1).

Methods: Seventy-three patients with localized Ewing sarcoma of bone aged < 30 years were included.