Negative central activity in extremely preterm newborns: EEG characterization and relationship with brain injuries and neurodevelopmental outcome.

Objective: To characterize Negative Central Activity (NCA), an overlooked electroencephalographic activity of preterm newborns and investigate its relationship with brain injuries, dysfunction, and neurodevelopmental outcome.

Methods: 109 preterm infants (23-28 weeks) were retrospectively included. NCA were selected at the negative peak on EEG.