Publications by authors named "Julie Carrara"
Article Synopsis
- The study investigates the effects of SARS-CoV-2 infection in pregnant women during their 2nd and 3rd trimesters, focusing on outcomes for both mothers and newborns during the first two COVID-19 waves in Paris from April 2020 to January 2021.
- Conducted in 10 maternity hospitals, the research included 2,410 pregnant women, with 310 testing positive for the virus, mostly around 28 to 37 weeks of gestation, and found that many could be treated as outpatients, while 23% required hospitalization.
- Key findings revealed that multiparous women were more likely to have serious outcomes such as preterm delivery and an
Article Synopsis
- Oxytocin can shorten labor but may cause complications, leading researchers to investigate if stopping the drug during labor affects neonatal outcomes.
- The STOPOXY trial, conducted in 21 French maternity units, randomly assigned participants to either stop or continue oxytocin infusion after reaching 6 cm dilation, measuring neonatal morbidity based on specific health indicators at birth.
- The study included 2,170 eligible participants, finding no significant difference in neonatal morbidity between the two groups, suggesting that discontinuing oxytocin may not increase risks for newborns.
Pregnancy is a particularly risky period in the life of patients with sickle cell disease (SCD). Physiological changes during pregnancy increase the risk of vaso-occlusive crises (VOC), acute chest syndrome, venous thromboembolic events, and infections. This concerns haemoglobin (Hb) S/C and S/β-thalassaemia patients as much than S/S or S/β-thalassaemia patients.
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- In 2020, the SARS-CoV-2 virus emerged in China, posing significant health risks, especially for pregnant women, leading to complications that can increase maternal and neonatal mortality.
- Research indicated potential maternal-fetal transmission of the virus and identified placental abnormalities, termed placentitis, which could disrupt placental functions and fetal heart rate monitoring.
- A study analyzed data from 17 mothers with SARS-CoV-2 infections; through this, clinicians discovered a high incidence of coagulopathy in mothers and noted that all fetuses were delivered through emergency cesarean sections, with one neonatal death recorded due to complications related to the infection.
non-hemorrhagic adrenal infarction (NHAI) is a rare cause of acute abdominal/flank pain during pregnancy; in order to ensure prompt and appropriate treatment, this diagnosis should not be overlooked. This case series highlights pertinent imaging findings, including ultrasounds (USs), computed tomography (CT), and magnetic resonance imaging (MRI) of recent NHAI cases. we compiled all consecutive NHAI cases from two university hospitals over a two-year period and checked the relevant clinical, laboratory, and imaging findings.
View Article and Find Full Text PDFSARS-COV-2 IgG antibody response in pregnant women at delivery.
J Gynecol Obstet Hum Reprod
September 2021
Article Synopsis
- A study called COVIPREG in France looks at how many pregnant women had COVID-19 during delivery and how it affects them and their babies.
- The study tested 529 pregnant women at a hospital to see how many had antibodies against the virus; only 25 women tested positive, making it about 4.7% of the group.
- The findings show that, four months into the pandemic in Paris, not many pregnant women had the virus, which is important for future research on COVID-19 effects during pregnancy.
Background: To fight the COVID-19 pandemic, lockdown has been decreed in many countries worldwide. The impact of pregnancy as a severity risk factor is still debated, but strict lockdown measures have been recommended for pregnant women.
Objectives: To evaluate the impact of the COVID-19 pandemic and lockdown on the seroprevalence and circulation of SARS-CoV-2 in a maternity ward in an area that has been significantly affected by the virus.
Article Synopsis
- Amniocentesis and chorionic villus sampling are key prenatal diagnostic procedures with a small miscarriage risk of about 0.5%, and a training model for these procedures has been developed and evaluated using simulation-based learning for obstetricians-gynecologists.
- A preliminary study was conducted through an anonymous online survey sent to 82 trained obstetricians-gynecologists to assess whether simulation training impacted their professional practices.
- Out of 48 respondents, 98% felt the training significantly influenced their work, with half deeming the impact major, and 60% now affiliated with a Multidisciplinary Center for Prenatal Diagnosis, indicating the training's effectiveness.
The particularity of pelvic actinomycosis lies in the difficulty of establishing the diagnosis prior to treatment. The objective of this retrospective bicentric study was to evaluate the pertinence and efficacy of the different diagnostic tools used pre- and post-treatment in a cohort of patients with pelvic actinomycosis. The following data were collected: clinical, paraclinical, type of treatment, and the outcome and pertinence of the two diagnostic methods, bacteriological or histopathological, were evaluated.
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- This study investigates the effectiveness of cell-free DNA (cfDNA) testing for detecting chromosomal abnormalities (trisomy 21, 18, and 13) in pregnant women with abnormal HCG and PAPP-A levels, indicating higher risks for complications.* -
- The analysis involved 477 women and showed that cfDNA testing had a 100% sensitivity and specificity for identifying trisomy 21, with other trisomies detected as well, contributing to its reliability as a screening tool.* -
- Additionally, the study aimed to assess cfDNA's role in predicting vascular complications during pregnancy, finding a few cases of hypertension among the participants.*
Management of Cytomegalovirus Seroconversion during Pregnancy in France.
Fetal Diagn Ther
November 2016
Introduction: Guidelines for the management of cytomegalovirus (CMV) infection of the fetus are rare. Our main objective was to evaluate how health care practitioners in France manage cases of CMV seroconversion during pregnancy.
Material And Methods: A questionnaire was e-mailed to health care practitioners potentially concerned by CMV seroconversion during pregnancy.