Dysfunctional plasmalogen dynamics in the plasma and platelets of patients with schizophrenia.

Background: Based upon the concept of a prodromal risk syndrome for first psychosis, intense efforts are being applied to define potential biomarkers of disease onset in schizophrenia. One such tentative biomarker may be plasmalogens, complex structural glycerophospholipids that serve multiple functions in all cells.

Methods: To further investigate this possibility, we undertook a lipidomics analysis of choline and ethanolamine plasmalogens in the plasma and platelets of 23 patients with schizophrenia and 27 age-matched controls.

Circulating plasmalogen levels and Alzheimer Disease Assessment Scale-Cognitive scores in Alzheimer patients.

Background: Plasmalogens, which are key structural phospholipids in brain membranes, are decreased in the brain and serum of patients with Alzheimer disease (AD). We performed this pilot study to evaluate the relation between the levels of circulating plasmalogens and Alzheimer Disease Assessment Scale-Cognitive (ADAS-Cog) scores in patients with AD.

Methods: We evaluated participants' ADAS-Cog scores and serum plasmalogen levels.

Influence of different relative intensities on power output during the hang power clean: identification of the optimal load.

The influence of different relative intensities on power output was investigated in the present study in order to identify the optimal load that maximizes power output during the hang power clean. Fifteen men (age: 22.1 +/- 2.