Publications by authors named "Julie A Adams"

Human-robot teams collaborating to achieve tasks under various conditions, especially in unstructured, dynamic environments will require robots to adapt autonomously to a human teammate's state. An important element of such adaptation is the robot's ability to infer the human teammate's tasks. Environmentally embedded sensors (e.

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Human-machine teams are deployed in a diverse range of task environments and paradigms that may have high failure costs (e.g., nuclear power plants).

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Current soft robotic arms commonly follow traditional-i.e. hard-robot design conventions.

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Current soft robotic arms commonly follow traditional - i.e., hard - robot design conventions.

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Information about a patient's state is critical for hospitals to provide timely care and treatment. Prior work on improving the information flow from emergency medical services (EMS) to hospitals demonstrated the potential of using automated algorithms to detect clinical procedures. However, prior work has not made effective use of video sources that might be available during patient care.

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Clinical documentation in the pre-hospital setting is challenged by limited resources and fast-paced, high-acuity. Military and civilian medics are responsible for performing procedures and treatments to stabilize the patient, while transporting the injured to a trauma facility. Upon arrival, medics typically give a verbal report from memory or informal source of documentation such as a glove or piece of tape.

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Understanding a patient's state is critical to providing optimal care. However, information loss occurs during patient hand-offs (e.g.

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A bis(cyclam)-capped cholesterol lipid designed to bind C-X-C chemokine receptor type 4 (CXCR4) was synthesised in good overall yield from 4-methoxyphenol through a seven step synthetic route, which also provided a bis(cyclam) intermediate bearing an octaethyleneglycol-primary amine that can be easily derivatised. This bis(cyclam)-capped cholesterol lipid was water soluble and self-assembled into micellar and non-micellar aggregates in water at concentrations above 8 μM. The bioactivity of the bis(cyclam)-capped cholesterol lipid was assessed using primary chronic lymphocytic leukaemia (CLL) cells, first with a competition binding assay then with a chemotaxis assay along a C-X-C motif chemokine ligand 12 (CXCL12) concentration gradient.

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We reviewed the available literature on measuring human performance to evaluate human-system interfaces (HSIs), focused on high-fidelity simulations of industrial process control systems, to identify best practices and future directions for research and operations. We searched the available literature and then conducted in-depth review, structured coding, and analysis of 49 articles, which described 42 studies. Human performance measures were classified across six dimensions: task performance, workload, situation awareness, teamwork/collaboration, plant performance, and other cognitive performance indicators.

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Background: Those stimuli that together promote the survival, differentiation and proliferation of the abnormal B-lymphocytes of chronic lymphocytic leukaemia (CLL) are encountered within tissues, where together they form the growth-supporting microenvironment. Different tissue-culture systems promote the survival of the neoplastic lymphocytes from CLL, partly replicating the in vivo tissue environment of the disorder. In the present study, we focussed on the initial adaptive changes to the tissue culture environment focussing particularly on migratory behaviour and cellular interactions.

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We have investigated the effect of cloretazine (VNP40101M or Laromustine), a novel sulfonylhydrazine alkylating agent with significant antileukaemic activity, alone, or combined with cytarabine or daunorubicin, on the proliferation, viability and apoptosis of cell lines and acute myeloid leukaemia blast cells in vitro. Cloretazine alone induced a concentration-dependent inhibition of proliferation, reduction in cell viability and an increase in apoptosis in all samples tested. Combinations of cloretazine with varying concentrations of cytarabine or daunorubicin further enhanced these inhibitory effects, suggesting VNP40101M may have a role in combined low dose chemotherapy regimes especially in the elderly.

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In this correspondence, we introduce our work on sketch understanding, focusing here on the analysis of a sketched route map. A route map is drawn to help someone navigate along a path for the purpose of reaching a goal. A hand-sketched route map does not generally contain complete map information and is not necessarily drawn to scale, but yet it contains the correct qualitative information for route navigation.

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