Publications by authors named "Juliano Carlo Rufino Freitas"

The leaves of Phyllanthus niruri L. are used in folk medicine in many countries to treat various diseases. However, despite the enormous therapeutic potential, use of the plant is contraindicated during pregnancy and breastfeeding.

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Maternal diet plays a crucial role in offspring development, directly affecting neural development and gut microbiota composition. This study aimed to assess if baru almond and oil (Dipteryx alata Vog.) could modulate intestinal microbiota, brain fatty acid profile, and enhance memory in offspring of rats treated during early life stages.

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This study evaluated the influence of maternal consumption of pequi pulp and nuts during pregnancy and lactation on reflex and somatic maturation and memory performance in rat offspring. The pups were divided into three groups: Control, treated with distilled water; a Pulp group and a Nuts group, treated with 2000 mg/kg of body weight of pequi pulp and nuts, respectively. Reflex and somatic maturation of the offspring were evaluated during lactation.

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Article Synopsis
  • - The study focused on creating and analyzing aroeira leaf flour (from Schinus terebinthifolius) using freeze-drying and air circulation drying methods, examining various characteristics such as technological, physical, and nutritional properties.
  • - Physico-chemical properties were assessed, revealing low moisture content, substantial levels of essential nutrients (like proteins and carbohydrates), and the presence of beneficial compounds such as phenolics and flavonoids, which contribute to antioxidant activity.
  • - Microscopy showed that the flour has a unique sponge-like structure, and due to its rich nutrient profile and bioactive compounds, aroeira leaf flour could be beneficial in food applications for improving nutritional value.
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The Pequi fruit (), typical of the Brazilian or savannah, is a source of essential fatty acids, carotenoids, and phenolic compounds. The aim of this study was to analyze the effects of consuming this fruit on anxiety behavior and lipid peroxidation in the brains of rats whose mothers were treated (by gavage) during pregnancy and lactation with Pequi fruit (pulp or nuts) at 2000 mg/kg of body weight. Anxiety parameters were assessed using the open field (OF), elevated plus maze (EPM), and light/dark box (LDB) tests.

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The objective was to evaluate the effects of the consumption of a mix of baru almond and goat whey on memory performance and anxiety parameters related to the intestinal health of rats treated during aging. The animals were divided into three groups and treated by gavage for 10 weeks (n = 10/each group): Control (CT) - distilled water; Baru almond (BA) - 2000 mg of baru/kg of body weight; and Baru + Whey (BW) - 2000 mg of baru + 2000 mg of goat milk whey/kg of body weight. Anxiety behavior, memory, brain fatty acid profile and fecal microbiota were measured.

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Ethnopharmacological Relevance: Phyllanthus niruri L. (Phyllanthaceae) is a plant used in traditional medicine, mainly to treat kidney stones. However, the effects of maternal exposure to P.

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