Structured Mobilization for Critically Ill Patients: A Pragmatic Cluster-randomized Trial.

Small trials and professional recommendations support mobilization interventions to improve recovery among critically ill patients, but their real-world effectiveness is unknown. To evaluate a low-cost, multifaceted mobilization intervention. We conducted a stepped-wedge cluster-randomized trial across 12 ICUs with diverse case mixes.

Circulating angiogenic cell population responses to 10 days of reduced physical activity.

Circulating angiogenic cells (CACs) are a diverse group that have been identified as predictors of cardiovascular health and are inversely proportional to cardiovascular disease (CVD) outcomes. Inactivity is a growing concern in industrialized nations and is an independent risk factor for CVD. There is limited evidence regarding the impact of reduced physical activity (rPA) on different CAC populations.