The risky business of advanced paternal age: neurodevelopmental and psychosocial implications for children of older fathers.

The last several decades are notable for an increase in the percentage of births attributable to men in their 40s and 50s. There is general recognition of offspring health risks related to advanced maternal age, however, fewer patients and providers are informed about the impacts of advanced paternal age (APA). This review examined the literature investigating the association between APA and offspring outcomes, specifically, neurodevelopmental, psychiatric, academic, and behavioral impairment, the impact of paternal health decline and death, and the influence of age on parenting behaviors.

Is it time to establish age restrictions in ART?

Providers specializing in reproductive medicine are treating increasing numbers of women pursuing parenthood in their 40s, 50s, and beyond. The rise in later-life parenting can be linked to factors ranging from the advent of assisted reproductive technologies and donor oocytes to the highly publicized pregnancies of older celebrities. We explore the medical and psychosocial implications of this trend for both older parents and their children.

Donor conception from the viewpoint of the child: positives, negatives, and promoting the welfare of the child.

Use of donor egg and donor sperm has made parenthood a possibility for many who could not achieve it through natural conception. The use of donor gametes may also permit prospective parents to mitigate a number of health problems for the hoped-for child. Promoting the welfare of the hoped-for child, however, includes not only the consideration of good physical health but also necessitates consideration of psychological, emotional, and social well-being.

Follow-up assessment of excluded oocyte donor candidates.

Aim: In 2005 16,161 fresh and frozen egg donation embryo transfer cycles were performed in the U.S.A.

Comparative assessment of pre- and post-donation attitudes towards potential oocyte and embryo disposition and management among ovum donors in an oocyte donation programme.

Background: In anonymous oocyte donation programmes, the disposition of retrieved oocytes and subsequent embryo management are at the discretion of the IVF programme and the oocyte recipients, as donors waive all rights following their donation. Nonetheless, donors are routinely made aware of ways in which oocytes and resulting embryos may be used and elect to proceed with the process even in the presence of reservations to some clinical scenarios before their donation. The aim of our study was to examine oocyte donors' attitudes to oocyte and embryo disposition and management and how initial reservations change over the course of the donation process.

Assessment of wishes regarding disposition of oocytes and embryo management among ovum donors in an anonymous egg donation program.

Revealing possible clinical scenarios to potential anonymous donors for their donated oocytes appears to uncover ambivalence in the majority of prospective candidates about their donation and unwillingness in some to proceed. Full disclosure to a prospective donor candidate of the program's policies for directives of donated oocytes and embryo management emphasizes the importance of the informed consent process and how it may affect the decision to donate.