Significance: The findings of this study indicate that patients could simultaneously be offered the individualized optical correction of wavefront-guided (WFG) lenses and the superior comfort afforded by polymer coatings. This could be helpful to patients with ectasia suffering ocular dryness or dependent on scleral lenses for lengthy periods of wear.
Purpose: Wavefront-guided scleral lenses target lower- and higher-order aberrations of individual eyes using submicrometer-level contours in the anterior lens surface.