Publications by authors named "Juliane Brandes"
Article Synopsis
- The study evaluated the metyrapone short test for assessing the hypothalamic-pituitary-adrenal (HPA) axis's function in patients with potential adrenal insufficiency.
- 44 patients were recruited and divided into response groups based on their 11-deoxycortisol levels, with various analytical methods utilized for metabolite profiling.
- Results showed distinct hormonal differences between the groups and highlighted the test's high diagnostic accuracy, suggesting that liver metabolites may play a role in the HPA axis's acute stress response.
Obesity and type 2 diabetes (T2D) show an increased risk for a severe COVID-19 disease. Treatment with DPP4 inhibitor (DPP4i) results in reduced mortality and better clinical outcome. Here, we aimed to identify potential mechanisms for the observed DPP4i effect in COVID-19.
View Article and Find Full Text PDFThe molecular foundation of chronic inflammatory diseases (CIDs) can differ markedly between individuals. As our understanding of the biochemical mechanisms underlying individual disease manifestations and progressions expands, new strategies to adjust treatments to the patient's characteristics will continue to profoundly transform clinical practice. Nutrition has long been recognized as an important determinant of inflammatory disease phenotypes and treatment response.
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