Publications by authors named "Juliana de Matos Maconetto"
Background And Objectives: Bone marrow mesenchymal stromal cells (BM-MSCs) are key elements of the hematopoietic niche and participate in the regulatory mechanisms of hematopoietic stem cells (HSCs). Hematological diseases can affect MSCs and their functions. However, the dysregulations caused by sickle cell disease (SCD) are not fully elucidated.
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- * By the fourth week of 2022, while testing numbers declined, the positivity rate stayed high, showing that 60% of individuals tested positive, with infections in younger children increasing from 2.8% to 9.2%.
- * The most common variant found was Omicron BA.1 (74.5%), with BA.2 showing signs of sustained transmission, indicating notable trends in the spread and evolution of this variant among the younger population.
From a country with one of the highest SARS-CoV-2 morbidity and mortality rates, Brazil has implemented one of the most successful vaccination programs. Brazil's first model city vaccination program was performed by the CoronaVac vaccine (Sinovac Biotech) in the town of Serrana, São Paulo State. To evaluate the vaccination effect on the SARS-CoV-2 molecular dynamics and clinical outcomes, we performed SARS-CoV-2 molecular surveillance on 4375 complete genomes obtained between June 2020 and April 2022 in this location.
View Article and Find Full Text PDFIt has been suggested that the bone marrow microenvironment harbors two distinct populations of mesenchymal stromal cells (MSC), one with a perivascular location and other present in the endosteum. A better understanding of the biology of these MSC subsets has been pursued in order to refine its clinical application. However, most comparative characterizations of mouse MSC have been performed in normoxia.
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