Ventilator hyperinflation associated with flow bias optimization in the bronchial hygiene of mechanically ventilated patients.

Background: Ventilation configurations are of great clinical importance for adequate outcomes in mechanically ventilated patients, and they may even be used as specific physical therapy techniques.

Objectives: To compare the effectiveness of lung hyperinflation through mechanical ventilation (HMV) with HMV plus flow bias optimization regarding respiratory mechanics, hemodynamics, and volume of secretion.

Methods: Patients mechanically ventilated > 24 h were included in this randomized crossover clinical trial.