Potentially Pathogenic Multidrug-Resistant in Lamb Meat.

Extended-spectrum cephalosporin (ESC) resistance remains a threat since ESC are important antimicrobials used to treat infections in humans and animals. is an important source of ESC-resistance genes, such as those encoding extended-spectrum β-lactamases (ESBLs). is a common commensal of lambs.

Dissemination of Multidrug-Resistant Commensal in Feedlot Lambs in Southeastern Brazil.

Antimicrobial resistance (AR) is a public health issue since it limits the choices to treat infections by in humans and animals. In Brazil, the ovine meat market has grown in recent years, but studies about AR in sheep are still scarce. Thus, this study aims to investigate the presence of AR in isolated from lambs during feedlot.

Characterization of the microtranscriptome of macrophages infected with virulent, attenuated and saprophyte strains of Leptospira spp.

Leptospirosis is a bacterial zoonosis, caused by Leptospira spp., that leads to significant morbidity and mortality worldwide. Despite considerable advances, much is yet to be discovered about disease pathogenicity.

Transcriptome datasets of macrophages infected with different strains of spp.

The datasets reported herein provide information about microarray experiment of macrophage cell line J774A.1 infected with three different strains of . Transcriptomic profiles were generated using Affymetrix® Mouse Gene 2.

IL-6 and TNF-alpha production during active canine visceral leishmaniasis.

We investigated the production of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) during canine visceral leishmaniasis (VL) to gain a better understanding of the role of such multi-functional cytokines in parasite resistance. IL-6 and TNF-alpha levels were measured by capture ELISA in sera from 8 healthy dogs from a non-endemic area (control group) and in sera from 16 dogs from Araçatuba, SP, Brazil, an area endemic for leishmaniosis. The dogs from the endemic area were selected by positive ELISA serology against total Leishmania chagasi antigen, positive spleen imprints for Leishmania, and the presence of at least three clinical signs associated with active visceral leishmaniasis (fever, dermatitis, lymphoadenopathy, onychogryphosis, weight loss, cachexia, locomotory difficulty, conjunctivitis, epistaxis, hepatosplenomegaly, edema, and apathy).

Araçatuba virus: a vaccinialike virus associated with infection in humans and cattle.

We describe a vaccinialike virus, Araçatuba virus, associated with a cowpoxlike outbreak in a dairy herd and a related case of human infection. Diagnosis was based on virus growth characteristics, electron microscopy, and molecular biology techniques. Molecular characterization of the virus was done by using polymerase chain reaction amplification, cloning, and DNA sequencing of conserved orthopoxvirus genes such as the vaccinia growth factor (VGF), thymidine kinase (TK), and hemagglutinin.