Publications by authors named "Juliana Pena Lopez"
Diabetic nephropathy is the primary cause of morbidity in type 2 diabetes mellitus (T2DM) patients. New data indicate that hypertension, a common comorbidity in T2DM, can worsen outcomes of diabetic nephropathy. While metformin is a commonly prescribed drug for treating type 2 diabetes, its blood pressure regulating ability is not well documented.
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- * The research investigated the lipid profiles of urinary EVs from aged mice in both inactive and active phases and found differences, particularly an increase in specific lipids in active phase EVs.
- * An ENaC inhibitor reduced blood pressure in aged male mice, and active-phase uEVs enhanced specific cellular responses indicating a relationship between lipid raft organization and blood pressure regulation in aging.