Pediatr Crit Care Med
February 2024
Objective: Evaluate the efficacy of tranexamic acid in reducing bleeding in patients undergoing total knee arthroplasty.
Methods: 101 patients were randomized into two groups: the tranexamic acid group ( = 51) and the placebo group ( = 50). Patients were compared regarding the following parameters: reduction of hemoglobin, total estimated blood loss, drain output, and postoperative blood transfusion rate.