Publications by authors named "Juliana Oliveira Martins"
Background: Hemolysis due to ABO incompatibility is an important differential diagnosis in newborns presenting with jaundice. Clinical studies evaluating ABO hemolytic disease of fetus and newborn (ABO-HDFN) question the diagnostic value of the direct antiglobulin test (DAT) in this situation.
Goals: To determine the clinical and laboratorial findings associated with the occurrence of ABO-HDFN and to evaluate the accuracy of DAT as a diagnostic tool.
Article Synopsis
- The study focuses on two cases of maternal anti-Fc-gamma-receptor-IIIb isoimmunization that did not show neonatal alloimmune neutropenia (NAIN) symptoms, highlighting the necessity of neutrophil isolation for diagnosing autoimmune conditions.
- Researchers compared two neutrophil isolation methods: immunomagnetic negative selection (IMNS) and traditional dextran/Ficoll, finding IMNS significantly produced more neutrophils in less time, despite being costlier.
- The findings underscore the importance of recognizing asymptomatic cases that could lead to severe neutropenia and validate IMNS as a superior method for neutrophil isolation in serological assays.
Introduction: The Band 3 is a red blood cell protein that carries the Di and Di antigens from the Diego blood system. The SLC4A1 gene encodes Band 3; Band 3 Memphis is a polymorphism of normal Band 3 and has two variants, but only the variant II carries the Di antigen.
Objectives: Describe the frequencies of the DI*A and DI*B alleles and the Band 3 Memphis among blood donors, sickle cell disease (SCD) patients and Amazonian Indians.
Introduction: Autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and autoimmune neutropenia (AIN) are reported in the literature after liver, intestinal, heart, pancreas, and kidney transplants. We report a case of autoimmune pancytopenia (AIHA, AIN and ITP) 9 years after liver transplantation with confirmed erythrocyte and neutrophil auto-antibodies.
Case Report: A 49 years old man was admitted to our hospital presented with dysentery and fever, with history of liver transplantation in 2008.
Background: Alloantibodies against human neutrophil antigens (HNA) resulting from allogeneic exposure may be associated with transfusion-related acute lung injury and immune neutropenia. Understanding the risk factors for the formation of such antibodies could have a great impact on the adoption of measures to prevent potentially fatal transfusion reactions. The aim of the study was to determine the prevalence of anti-HNA alloantibodies in non-transfused pregnant women with and without red blood cell (RBC) alloantibodies.
View Article and Find Full Text PDFBackground: Neonatal alloimmune neutropenia results from maternal alloimmunization to human neutrophil antigens. The alloantibodies involved in neonatal alloimmune neutropenia are against human neutrophil antigens HNA-1a, HNA-1b, HNA-1c, HNA-1d, HNA-2, HNA-3a, HNA-4a, HNA-4b, and HNA-5a; however, to date, antibodies specific to HNA-3b have not been reported.
Study Design And Methods: Blood samples from 10,000 unselected neonates were analyzed, resulting in the selection of 88 neutropenic newborns (neutrophil count <1.