Publications by authors named "Juliana Ochoa"
Myeloid-derived suppressor cells as a potential biomarker for recurrent pregnancy loss and recurrent implantation failure: Increased levels of MDSCs in recurrent reproductive failure.
Am J Reprod Immunol
November 2023
Problem: Recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) represent distinct clinical conditions with established definitions, both of which have been linked to an underlying pro-inflammatory state. This study aimed to explore the levels of monocytic-myeloid-derived suppressor cells (M-MDSCs) and regulatory T cells (T ) in a cohort of RPL and RIF women and their potential contribution to RPL and RIF.
Method Of Study: One hundred and eight non-pregnant women were evaluated: 40 RPL, 41 RIF, and 27 fertile healthy controls (HC).
Article Synopsis
- * A study on the sublingual administration of a heat-inactivated polybacterial preparation called MV130 showed it significantly reduces respiratory infections in RRTI patients, but the underlying immunological mechanisms remained unclear.
- * Research found that MV130 enhances immune responses by stimulating specific pathways in human dendritic cells, leading to improved immune responses in both patients and healthy individuals, suggesting it could be developed as an alternative treatment for recurrent infections.
Quantification of T-cell receptor excision circles (TRECs) for newborn screening for SCID has advanced the diagnosis of severe combined immune deficiency (SCID). However, it has led to the identification of infants with T cell lymphopenia without known cause. The clinical characteristics, appropriate laboratory monitoring, and outcomes of patients remain unclear.
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