Publications by authors named "Juliana O Tonaki"
Prospective Randomized Phase 2 Trial of Hypofractionated Stereotactic Radiation Therapy of 25 Gy in 5 Fractions Compared With 35 Gy in 5 Fractions in the Reirradiation of Recurrent Glioblastoma.
Int J Radiat Oncol Biol Phys
July 2024
Article Synopsis
- The study aimed to evaluate if reirradiation of recurrent glioblastoma with higher doses of hypofractionated stereotactic radiation therapy (HSRT) would improve patient outcomes compared to a lower dose while keeping side effects manageable.
- A randomized trial involved 40 patients who were assigned to receive either 25 Gy in 5 fractions or 35 Gy in 5 fractions. Results showed no significant difference in progression-free survival (PFS) or overall survival (OS) between the two groups.
- Despite a slight numerical increase in severe necrosis in the higher dose group, it was concluded that the lower dose (25 Gy/5 fx) should be the standard for HSRT due to similar effectiveness and potentially lower toxicity
Patient's perceptions of oral and oropharyngeal cancer diagnosis disclosure: communication aspects based on SPIKES protocol.
Oral Surg Oral Med Oral Pathol Oral Radiol
April 2023
Objective: Breaking bad medical news is a complex task of clinical practice. The manner in which this is done has a significant impact on patients. This study aimed to assess patient's perceptions regarding oral and oropharyngeal cancer diagnosis disclosure according to the "SPIKES" protocol.
View Article and Find Full Text PDFObjective: To evaluate whether the coronavirus disease 2019 has increased anxiety, depression, and distress levels in head and neck cancer (HNC) patients undergoing radiotherapy (RT).
Methods: In this cross-sectional study, RT-HNC patients were surveyed using the Hospital Anxiety and Depression Scale (HADS) for anxiety and depression and the distress thermometer (DT) for distress. HADS scores were compared with data pre-COVID-19.
The impact of an educational video about radiotherapy and its toxicities in head and neck cancer patients. Evaluation of patients' understanding, anxiety, depression, and quality of life.
Oral Oncol
July 2020
Objectives: Head and neck radiotherapy can cause several toxicities, and its management has important treatment implications. Proper information about treatment is crucial to assist patients by preparing them and enhancing their ability to manage their illness. Thus, this study aimed to verify the impact of an educational video on the improvement of the patient's understanding, satisfaction, quality of life, and influence on their emotional state in different moments of treatment.
View Article and Find Full Text PDFStrategies for communicating oral and oropharyngeal cancer diagnosis: why talk about it?
Oral Surg Oral Med Oral Pathol Oral Radiol
April 2020
Objective: This review aimed to explore the paradigms of disclosing a cancer diagnosis with a focus on oral and oropharyngeal cancer and patient-related considerations.
Study Design: A search of MEDLINE, Embase, and Scopus was conducted using the following keywords: oral cancer; mouth lesions; oncology; breaking bad news; truth disclosure; and communication skills training. English and Spanish language studies published through October 2019 were included.