Is pulmonary arterial hypertension associated with schistosomiasis distinct from pulmonary arterial hypertension associated with portal hypertension?

Pulmonary arterial hypertension associated with schistosomiasis (SchPAH) and pulmonary arterial hypertension associated with portal hypertension (PoPAH) are lung diseases that develop in the presence of liver diseases. However, mechanistic pathways by which the underlying liver conditions and other drivers contribute to the development and progression of pulmonary arterial hypertension (PAH) are unclear for both etiologies. In turn, these unknowns limit certainty of strategies to prevent, diagnose, and reverse the resultant PAH.

Degradation of Staphylococcus aureus Biofilm Using Hydrolytic Enzymes Produced by Amazonian Endophytic Fungi.

Microbial biofilms can cause serious health problems, since, due to their persistent character, they often function as spreaders of contaminants. Hydrolytic enzymes have a number of industrial applications and have been indicated as an alternative to the traditional chemical methods that are used to eradicate microbial biofilms. In this study, we evaluated the ability of enzymatic extracts produced by endophytic fungi isolated from the Amazonian species Myrcia guianensis to remove Staphylococcus aureus biofilms.

Chemical Composition and Bactericidal Activity of the Essential Oils of Four Species of Annonaceae Growing in Brazilian Amazon.

A study was conducted to determine the chemical composition and the antibacterial activity of essential oils from Bocageopsis multiflora (Mart.) R.E.

Hemochromatosis simulating rheumatoid arthritis: a case report.

This is a report of a patient who had a previous diagnosis of rheumatoid arthritis, nonerosive, rheumatoid factor negative, that despite the therapeutic approach presented progressive worsening of the articular and general condition. After extensive research, she had a diagnosis of hemochromatosis. Joint symptoms are common manifestations in hemochromatosis.

ANCA associated vasculitis and chronic lymphocytic leukemia: a rare association.

The aim of the present work is to discuss the report of a patient who had simultaneous diagnosis of two rare diseases, vasculitis related to antineutrophil cytoplasmic antibodies and chronic lymphocytic leukemia. Both are diseases that may be multisystemic and thus cause diagnostic confusion. In this case, the patient had renal, pulmonary, hematological, and ocular symptoms, which could be secondary to vasculitis both as to leukemia.

Cardiovascular mortality and its relation to socioeconomic levels among inhabitants of São José do Rio Preto, São Paulo state, Brazil.

Objective: To analyze cardiovascular mortality indicators in São José do Rio Preto--a city in the State of São Paulo, Brazil--and to evaluate the municipality's mortality rates by socioeconomic levels.

Methods: Data used came from the Mortality Information System and from the Information and Computing Department of the federal governments Unified Health System (SUS). Standardized mortality rates and proportional cardiovascular mortality rates were calculated.