Publications by authors named "Juliana Kok"
Background: The management of post-operative pain and high levels of acute and chronic opioid use following total knee arthroplasty (TKA) and total hip arthroplasty (THA) remain challenges to the perioperative team. We performed a system-atic review and meta-analysis to determine the opioid sparing effects, analgesic effects, and safety profile of perioperative gabapentinoid usage in lower limb arthroplasty.
Methods: We searched multiple databases from inception until May 2019 and included randomized controlled trials (RCT) on perioperative gabapentinoids in lower limb arthroplasty.
Background: Pulmonary aspiration of gastric contents is recognized as a complication of anesthesia. To minimize that risk, anesthesiologists advised fasting for solid foods and liquids for an often prolonged period of time. However, 30 years ago, evidence was promulgated that fasting for clear liquids was unnecessary to ensure an empty stomach.
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- The demand for effective biomarkers in surgical vascular disease is rising, particularly for preoperative risk assessment, with the neutrophil-lymphocyte ratio (NLR) emerging as a strong candidate.
- A systematic review and meta-analysis of 14 studies involving 5,652 patients found that elevated NLR is linked to increased short-term and long-term mortality risk after vascular surgery.
- Despite its potential as a simple and accessible prognostic tool, variations in patient demographics and surgical types make direct comparisons across studies difficult, indicating a need for further investigation into NLR's effectiveness.
Background: The prognostic value of asymptomatic perioperative troponin rise in vascular surgery is unclear. We conducted this systematic review and meta-analysis to determine the significance of clinical and subclinical troponin elevation after vascular surgery.
Methods: We searched MEDLINE (Ovid), Embase (Ovid), and the Cochrane Library, without language restriction, from inception to May 2019 and included studies that reported associations between elevated postoperative troponin and short-term mortality, major adverse cardiac events (MACEs), or long-term mortality in a vascular surgery cohort.