Publications by authors named "Juliana Cuervo-Rojas"
Development of a diagnostic multivariable prediction model of a positive SARS-CoV-2 RT-PCR result in healthcare workers with suspected SARS-CoV-2 infection in hospital settings.
PLoS One
December 2024
Background: Despite declining COVID-19 incidence, healthcare workers (HCWs) still face an elevated risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. We developed a diagnostic multivariate model to predict positive reverse transcription polymerase chain reaction (RT-PCR) results in HCWs with suspected SARS-CoV-2 infection.
Methods: We conducted a cross-sectional study on episodes involving suspected SARS-CoV-2 symptoms or close contact among HCWs in Bogotá, Colombia.
Article Synopsis
- The study investigates how the immune responses (antibodies and CD4 T cells) to SARS-CoV-2 from natural infection and vaccination change over time, focusing on variants like Mu, Gamma, and Delta.
- It found that antibody levels decline after 6 months, particularly in mildly infected individuals, while those severely infected maintain higher levels; vaccination boosts antibody production but they also decrease over time.
- The cross-recognition of variants showed varying effectiveness, and prior exposure to the virus influenced the immune response, suggesting important considerations for future vaccine development against emerging variants.
Introduction: Late diagnosis of HIV (LD) increases the risk of morbidity, mortality, and HIV transmission. We used nationally representative data from population-based HIV impact assessment (PHIA) surveys in Malawi, Zambia, and Zimbabwe (2015-2016) to characterize adults at risk of LD and to examine associations between LD and presumed HIV transmission to cohabiting sexual partners.
Methods: We estimated the prevalence of LD, defined as CD4 count <350 cells/μL, among adults newly diagnosed with HIV during the surveys and odds ratios for associated factors.
Article Synopsis
- The study examined the incidence, prevalence, and factors related to SARS-CoV-2 infections among healthcare workers at a university hospital in Bogotá from March 2020 to February 2021.
- The cumulative incidence of infection was found to be 35.7% with a seroprevalence of 21.5%, highlighting a significant burden among workers.
- Factors contributing to a higher risk of infection included being a nurse, working in high-risk areas, being overweight or obese, and having close contact with COVID-19 patients, underscoring the need for improved preventative measures.
Background: Malawi spearheaded the development and implementation of Option B+ for prevention of mother-to-child transmission of HIV (PMTCT), providing life-long ART for all HIV-positive pregnant and breastfeeding women. We used data from the 2015-2016 Malawi Population-based HIV Impact Assessment (MPHIA) to estimate progress toward 90-90-90 targets (90% of those with HIV know their HIV-positive status; of these, 90% are receiving ART; and of these, 90% have viral load suppression [VLS]) for HIV-positive women reporting a live birth in the previous 3 years.
Methods: MPHIA was a nationally representative household survey; consenting eligible women aged 15-64 years were interviewed on pregnancies and outcomes, including HIV status during their most recent pregnancy, PMTCT uptake, and early infant diagnosis (EID) testing.
Cardiovascular risk factors and comorbidities in people living with HIV: A cross-sectional multicenter study from Colombia comorbidities in a Colombian PLWHIV population.
Int J STD AIDS
June 2022
Introduction: HIV is an independent risk factor for cardiovascular diseases (CVD). There is insufficient information regarding comorbidities and cardiovascular risk factors in the Colombian HIV population. The aim of this study is to describe the prevalence of cardiovascular risk factors and comorbidities in patients from the HIV Colombian Group VIHCOL.
View Article and Find Full Text PDFBackground: Control of the pediatric HIV epidemic is hampered by gaps in diagnosis and linkage to effective treatment. The 2015-2016 Malawi Population-based HIV impact assessment data were analyzed to identify gaps in pediatric HIV diagnosis, treatment, and viral load suppression.
Methods: In half of the surveyed households, children ages ≥18 months to <15 years were tested using the national HIV rapid test algorithm.
Objective: To evaluate the association of HIV infection and cumulative exposure to highly active antiretroviral therapy (HAART) with the presence and extent of coronary artery calcification (CAC).
Design: A cross-sectional study of 947 male participants (332 HIV-seronegative, 84 HAART-naive and 531 HAART-experienced HIV-infected) from the Multicenter AIDS Cohort Study.
Methods: The main outcome was CAC score calculated as the geometric mean of the Agatston scores of two computed tomography replicates.