Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR).

Introduction: Cigarettes containing nicotine (Nic) are a risk factor for the development of cardiovascular and metabolic diseases. We reported that Nic delivered via injections or e-cigarette vapor led to hepatic steatosis in mice fed with a high-fat diet. High-fructose corn syrup (HFCS) is the main sweetener in sugar-sweetened beverages (SSBs) in the US.

The role of Neurochemicals, Stress Hormones and Immune System in the Positive Feedback Loops between Diabetes, Obesity and Depression.

Type 2 diabetes mellitus (T2DM) and depression are significant public health and socioeconomic issues. They commonly co-occur, with T2DM occurring in 11.3% of the US population, while depression has a prevalence of about 9%, with higher rates among youths.

Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome.

The study of the intestinal or gut microbiome is a newer field that is rapidly gaining attention. Bidirectional communication between gut microbes and the host can impact numerous biological systems regulating immunity and metabolism to either promote or negatively impact the host's health. Habitual routines, dietary choices, socioeconomic status, education, host genetics, medical care and environmental factors can all contribute to the composition of an individual's microbiome.

The Combination of High-Fat Diet and Oral Marijuana Promotes the Development of Fibrosis in the Mouse Corpora Cavernosa.

Introduction: The link between cannabis use and erectile dysfunction remains unclear. Moreover, the effect of cannabis in tandem with current Western dietary habits is an area in male sexual health that has yet to be explored. This study seeks to investigate the impact of diet and cannabis on penile health in an animal model.

High Prevalence of Adrenal Remnant Tissue in Patients Undergoing Bilateral Adrenalectomy for Cushing's Disease.

Bilateral adrenalectomy (BLA) is a treatment option for patients with Cushing's Disease (CD) if transsphenoidal pituitary surgery fails or is not a therapeutic option. For most patients, BLA eliminates endogenous glucocorticoid and mineralocorticoid production, but for a small number of patients, endogenous secretion of adrenal hormones from adrenal tissue continues or recurs, leading to signs and symptoms of hypercortisolism. If adrenal tissue is confined to the adrenal bed, it is considered , while if it is outside the adrenal bed, it is considered .

A mouse model for chronic intermittent electronic cigarette exposure exhibits nicotine pharmacokinetics resembling human vapers.

Electronic cigarettes (E-cig) use is increasing rapidly, particularly among youths. Animal models for E-cig exposure with pharmacokinetics resembling human E-cig users are lacking. We developed an E-cig aerosol exposure system for rodents and a chronic intermittent delivery method that simulates E-cig users who vape episodically during wakefulness and abstain during sleep.

Patterns of physiological decline due to age and selection in Drosophila melanogaster.

In outbred sexually reproducing populations, age-specific mortality rates reach a plateau in late life following the exponential increase in mortality rates that marks aging. Little is known about what happens to physiology when cohorts transition from aging to late life. We measured age-specific values for starvation resistance, desiccation resistance, time-in-motion, and geotaxis in ten Drosophila melanogaster populations: five populations selected for rapid development and five control populations.

Juxta-articular Myxoma of the Temporomandibular Joint.

The juxta-articular myxoma represents a benign mesenchymal neoplasm that arises from tissue within or adjacent to a joint space. There have been a number of reported cases involving myxomas of the knee, shoulder, elbow, wrist, and hip. To our knowledge there, however, have been no reported cases of juxta-articular myxomas of the temporomandibular joint (TMJ).

Use of computer-assisted templates for placement of osteotomies in lateral gap arthroplasty.

Purpose: To evaluate the effectiveness of computer-generated surgical templates for precise bone removal in the treatment of temporomandibular joint (TMJ) ankylosis with a medially displaced condyle.

Materials And Methods: Patients found to have a medially displaced condylar head and lateral bony fusion from January 2012 through January 2014 were included in the study. ProPlan CMF 1.

Application of digital templates to guide total alloplastic joint replacement surgery with biomet standard replacement system.

Purpose: To design and manufacture digital templates to guide Biomet total alloplastic joint replacement surgery (Biomet, Warsaw, IN) and evaluate the clinical efficacy.

Materials And Methods: Six patients who underwent total alloplastic joint replacement surgery from November 2013 to March 2014 were included in this study. Before surgery, the Biomet standard prostheses were scanned and imported into the ProPlan CMF 1.

Modified temporomandibular joint disc repositioning with miniscrew anchor: part I--surgical technique.

Anterior disc displacement is one of the most common conditions affecting the temporomandibular joint. In the authors' previous publications, they reported on the basic technical elements of disc repositioning surgery. However, the present article presents some critical modifications that have allowed the safe and successful performance of this procedure during the past 3 years.

Improving health services for residents through community-based participatory research: a public housing leadership perspective.

Background: In response to feedback from a health forum, resident leaders of public housing in Washington, DC, were inspired to create a health survey for and by the residents.

Objective: The survey was designed to document residents' concerns about health, health care, and environmental threats. It also explored tobacco use and support for smoke-free housing.

Optimal foraging: The responses of Peromyscus leucopus to experimental changes in processing time and hunger.

Food density, degree of hunger prior to foraging, and food processing difficulty were varied in order to determine their effects on the diet diversity of captive Peromyscus leucopus foraging for buried seeds. No relationship was found between diet diversity and food density. However, diet diversity exhibited a significantly positive relationship with hunger, and a significantly negative relationship with seed processing time.