Publications by authors named "Julian R Avila"
Article Synopsis
- The study focuses on the Arabidopsis ERECTA (ER) receptor kinase, which regulates various developmental processes through receptor signaling.
- The C-terminal tail of the ER receptor (ER_CT) acts as an autoinhibitory element that prevents excessive receptor activity, and its removal leads to increased kinase activity during plant growth.
- Phosphorylation of ER_CT by the co-receptor BAK1 alters its structure, affecting interactions with inhibitors and ligases, thus enabling precise control over receptor activation and ensuring quick deactivation after signaling.
The study of cell-surface receptor dynamics is critical for understanding how cells sense and respond to changing environments. Therefore, elucidating the mechanisms by which signals are perceived and communicated into the cell is necessary to understand immunity, development, and stress. Challenges in testing interactions of membrane-bound proteins include their dynamic nature, their abundance, and the complex dual environment (lipid/soluble) in which they reside.
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