Development of the 'Sigue la Huella' physical activity intervention for adolescents in Huesca, Spain.

Engaging in physical activity (PA) on a regular and adequate basis generates considerable benefits for health. In developed countries, the time spent doing PA is decreasing, whilst sedentary time (ST) is increasing. A multicomponent school-based intervention programme, called 'Sigue la Huella' (Follow the Footprint), was developed to reduce sedentary lifestyles and increase PA levels.

Motivational Outcomes and Predictors of Moderate-to-Vigorous Physical Activity and Sedentary Time for Adolescents in the Sigue La Huella Intervention.

Purpose: The purpose of this study was to investigate the effects of the multicomponent Sigue la Huella intervention on selected motivational outcomes and whether any of these outcomes, in addition to relevant socio-demographic, biological, and behavioral factors, served as predictors of moderate-to-vigorous physical activity and sedentary time among participants through the intervention.

Method: This quasi-experimental, cohort study took place in four secondary schools in Huesca (Spain) during three academic years (students aged 12-15 years). Two schools were assigned to the experimental condition (n = 368) and two schools to the control condition (n = 314).

Effects of the 3-year Sigue la Huella intervention on sedentary time in secondary school students.

Background: To examine the effects of the Sigue la Huella (Follow the Footstep) intervention on adolescents' daily sedentary time (ST).

Methods: This quasi-experimental, cohort study took place in four secondary schools in Huesca (Spain) during the 2009-2010, 2010-2011 and 2011-2012 academic years (students aged 12-15 years). Two schools were assigned to the experimental condition (n = 368) and two schools to the control condition (n = 314).

Data for action: the use of formative research to design a school-based intervention programme to increase physical activity in adolescents.

Formative research is a critical step for the development of interventions aimed at changing behaviours, as is the case of physical activity. This process permits obtaining detailed information about the programme application context. 'Follow the Footstep' is a quasi-experimental and longitudinal study in secondary schools, the aim of which is to increase levels of physical activity among adolescents.

Empowering adolescents to be physically active: three-year results of the Sigue la Huella intervention.

Objective: To examine the effects of a school-based intervention called Sigue la Huella (Follow the Footstep) on adolescents' daily moderate-to-vigorous physical activity (MVPA).

Method: This quasi-experimental, cohort study took place in four secondary schools in Huesca (Spain) during the 2009-2010, 2010-2011, and 2011-2012 academic years (students aged 12-15 years). Two schools were assigned to the experimental condition (n=368) and two schools to the control condition (n=314).

Promising school-based strategies and intervention guidelines to increase physical activity of adolescents.

This narrative review describes the available scientific evidence regarding promising school-based strategies to increase physical activity of adolescents. We conducted a literature search for studies published up to 2011, regarding adolescent physical activity intervention studies that resulted in increased physical activity (regardless of measurement) and reviewed 52 intervention articles and 21 review articles. We identified several promising strategies and grouped into five broad intervention guidelines.

A novel RMRP mutation in a Spanish patient with cartilage-hair hypoplasia.

Cartilage-hair hypoplasia (CHH), or McKusick type metaphyseal chondrodysplasia, was first recognized as a distinct entity in the Old Order Amish in the USA, but was later identified in other groups, and found to be unusually frequent among Finns. CHH is highly pleiotropic with manifestations that include short stature, defective cellular immunity and predisposition to several cancers. CHH is caused by mutations in the RNA component of RNase MRP (RMRP, ribonuclease mitochondrial RNA processing) and is transmitted as an autosomal recessive trait.

[Immunologic recovery after 2-years on HAART in vertically HIV-infected children].

Background: Our purpose was to carry out an analysis of T cells subsets involved in the recovery of the immune system in vertically HIV-1-infected children, on highly active antiretroviral therapy (HAART) over more than 24 months.

Patients And Method: Seventeen HIV-1-infected children were studied: a) Res-group (HIV-1-infected children who were HAART-responders): 10 children in category C3 at entry in the study who, after more than 24 months on HAART, recovered CD4+ T cells (> 25% and 500 CD4+ T-cells/ml) and may control viral replicación, and b) non-Res group (HIV-1-infected children who did not respond to HAART): 7 children in category C3 at entry in the study who, after more than 24 months on HAART, did not recover CD4+ T-cells (< 15% or 200 CD4+ T-cells/ml) and did not control viral replication. As control group, 12 HIV-1-uninfected children with similar ages were included in the study.