Publications by authors named "Julian Boesch"
Front Physiol
September 2024
Article Synopsis
- - Multiple sclerosis (MS) is an autoimmune disease causing inflammation and damage in the central nervous system, leading to symptoms like muscle dysfunction that can affect mobility and quality of life.
- - Current treatments mainly focus on neuroinflammation, leaving a need for therapies targeting muscle function, as many people with MS experience skeletal muscle issues that can precede mobility-related disabilities.
- - Exercise, particularly aerobic and resistance training, is highlighted as an effective intervention to improve muscle strength, reduce fatigue, and enhance overall well-being in individuals with MS, emphasizing the importance of implementing these exercises early on.
Front Physiol
November 2022
Article Synopsis
- Musculoskeletal diseases are a major cause of mobility issues, often linked to muscle weakness, making resistance training a common treatment to boost strength.
- This study examines the chemerin pathway's role in inflammation and muscle function, finding that blocking a specific receptor (CMKLR1) can temporarily enhance strength but reduces endurance in mice.
- The research highlights the importance of CMKLR1 in muscle regeneration and contractility, suggesting potential for new drugs targeting this pathway to treat musculoskeletal and other diseases.
