Gut microbiota predicts severity and reveals novel metabolic signatures in acute pancreatitis.

Objective: Early disease prediction is challenging in acute pancreatitis (AP). Here, we prospectively investigate whether the microbiome predicts severity of AP (Pancreatitis-Microbiome As Predictor of Severity; P-MAPS) early at hospital admission.

Design: Buccal and rectal microbial swabs were collected from 424 patients with AP within 72 hours of hospital admission in 15 European centres.

Body impedance analysis to estimate malnutrition in inflammatory bowel disease patients - A cross-sectional study.

Objective: Malnutrition is a common clinical problem in patients with inflammatory bowel diseases (IBD). However, a gold standard for the detection of malnutrition in IBD patients is lacking.

Methods: A cross-sectional study to assess malnutrition in patients with IBD and healthy controls (HCs).

Does etiology of acute pancreatitis matter? A review of 391 consecutive episodes.

Context: Acute pancreatitis can be triggered by a variety of factors ranging from short lasting to sustained disruptions. It is plausible that the characteristics and course of disease differ among etiologies. Data distinguishing characteristics of patients with pancreatitis of biliary, alcoholic, idiopathic or other origin are scarce and conflicting.

Detrimental effect of high volume fluid administration in acute pancreatitis - a retrospective analysis of 391 patients.

Background: Early fluid resuscitation is recommended for the therapy of acute pancreatitis in order to prevent complications. There are, however, no convincing data supporting this approach.

Methods: We reviewed 391 consecutive cases of confirmed acute pancreatitis.