Thinner temporal peripapillary retinal nerve fibre layer in Stargardt disease detected by optical coherence tomography.

Purpose: To evaluate peripapillary retinal nerve fibre layer (RNFL) thickness measured by spectral domain optical coherence tomography (OCT) in patients with Stargardt disease (STGD).

Methods: A cross-sectional, monocentric, observational case-control study. Twenty patients (39 eyes) with ABCA4 mutations graded according to the Fishman STGD classification were included.

Ophthalmic Care in Nursing Homes for the Blind: A Growing Challenge.

Background: The demographic change in Germany will lead to an increase in irreversible age-related eye diseases. This will increase the need for specialised care facilities for visually impaired people. Due to reduced mobility, residents in such facilities often do not receive adequate ophthalmological care.

[Use of the Multidisciplinary Specialised Case Conference at the Freiburg Orbital Centre].

Background: The treatment of tumors increasingly takes place in specialised interdisciplinary centres. Therapeutic decisions are usually made at case conferences. Ophthalmologists, oromaximillofacial surgeons, ENT physicians, neurosurgeons, as well as pediatricians, radiotherapists and radiologists are all involved in the treatment of orbital diseases.

A Pilot Study on the Efficacy and Safety of 0.01% Atropine in German Schoolchildren with Progressive Myopia.

Introduction: Although the interest is growing in topical low-dose atropine to control myopia in schoolchildren worldwide, its use in children of European ancestry remains controversial and solid evidence is sparse. The Oxford Centre for Evidence Based Medicine (OCEBM) classifies the evidence for this therapy as level I for East Asian populations, but only level IV in non-Asian populations.

Methods: Fifty-six children, aged a median of 11 years (range 6-17), were analysed after 12 months of topical treatment with 0.

[Is the Patient Record Sufficient for Prescribing Low-Vision Magnification Aids or Is a Consultation in a Low-Vision Clinic Required?].

Background: Many visually impaired and blind patients regain reading ability by using magnification aids. They are tested and prescribed in a time-intensive consultation at our low-vision clinic. Thus, the question arises if it is possible to automate the selection and prescription of low-vision aids only on the basis of the patients' records.

Neuroprotection and neuroregeneration of retinal ganglion cells after intravitreal carbon monoxide release.

Purpose: Retinal ischemia induces apoptosis leading to neurodegeneration and vision impairment. Carbon monoxide (CO) in gaseous form showed cell-protective and anti-inflammatory effects after retinal ischemia-reperfusion-injury (IRI). These effects were also demonstrated for the intravenously administered CO-releasing molecule (CORM) ALF-186.