Radiologist Engagement as a Potential Barrier to the Clinical Translation of Quantitative Imaging for the Assessment of Tumor Heterogeneity.

Rationale And Objective: This study aims to identify potential barriers to the clinical implementation of quantitative imaging for the assessment of tumor heterogeneity.

Materials And Methods: An 18-month prospective observational study was undertaken in which the clinical implementation of computed tomography texture analysis (CTTA) as a technique for quantifying tumor heterogeneity in patients with non-small cell lung cancer was assessed using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework.

Results: Adopters of the technology comprised five specialists with dual accreditation in radiology and nuclear medicine supervising two trainees.