Publications by authors named "Julia Silberman"
Article Synopsis
- Flagella are crucial for the movement of pathogens like the Lyme spirochete Borrelia burgdorferi, but their production is costly and triggers immune responses, leading to complex regulatory systems controlling their gene expression.
- The study identifies the gene bb0268 (flgV) in B. burgdorferi as a structural component of the flagella, rather than the previously thought RNA-binding protein, which plays a significant role in flagellar assembly.
- FlgV is essential for producing functional flagella and affects the bacteria's motility and ability to infect hosts, highlighting its importance in the pathogen's life cycle, especially during infection phases.
Diabetes management demands precise monitoring of key biomarkers, particularly insulin (I) and glucose (G). Herein, we present a bioelectronic chip device that enables the simultaneous detection of I and G in biofluids within 2 min. This dual biosensor chip integrates aptamer-based insulin sensing with enzymatic glucose detection on a single platform, employing a four-electrode sensor chip.
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