Publications by authors named "Julia Sellares-Nadal"
VIM-type-producing Gram-negative bacteria (GNB) infections are difficult to treat. This is a retrospective single-center study of 34 patients who received cefiderocol for the treatment of VIM-type-producing GNB infections, including 25 spp., 7 , and 5 sp.
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- The study focuses on identifying adult patients, especially older adults, who are at low risk for central nervous system (CNS) infections, to potentially avoid unnecessary lumbar punctures (LP).
- Researchers analyzed data from 489 patients in the emergency room, finding that only 15.7% were diagnosed with CNS infections and identifying key factors that indicate a lower risk for these infections.
- Key factors such as being female, over 80 years old, having previous cognitive impairment, and lacking meningitis symptoms significantly predicted low risk, resulting in a diagnostic tool with a 98% positive predictive value for avoiding LP.
Purpose: The presence of a respiratory virus in patients with community-acquired pneumonia (CAP) may have an impact on the bacterial etiology and clinical presentation. In this study we aimed to assess the role of viral infection in the bacterial etiology and outcomes of patients with CAP.
Methods: We performed a retrospective study of all adults hospitalized with CAP between November 2017 and October 2018.
Infection after spinal instrumentation (IASI) by spp. is being more frequently reported. The aim of this study was to analyse the incidence, risk factors, clinical characteristics, and outcome of a spp.
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- Community-acquired pneumonia (CAP) is a common cause of hospitalizations, and a study was conducted to analyze how its epidemiology and outcomes have evolved over a decade due to factors like pandemics and vaccinations.
- Researchers compared data from two groups of patients diagnosed with CAP, one from 2007-2008 and another from 2017-2018, and examined their clinical outcomes and mortality rates.
- The study found that while the bacterial causes of CAP remained consistent over the years, there was a significant decrease in severe complications such as septic shock and bacteraemia, and influenza vaccination appeared to reduce mortality in the more recent period.
Background: Modulation of the immune system to prevent lung injury is being widely used against the new coronavirus disease (COVID-19). The primary endpoint was mortality at 7 days after tocilizumab administration. Secondary endpoints were admission to the intensive care unit, development of ARDS and respiratory insufficiency among others.
View Article and Find Full Text PDFWe report a case of a liver transplant performed in a patient with a history of SARS-CoV-2 infection who presented with a positive polymerase chain reaction test for SARS-CoV-2 on the day of transplant. The transplant procedure was performed without complications, and the patient did not develop symptoms after the initiation of immunosuppression. We also reviewed the literature for similar cases.
View Article and Find Full Text PDFBackground: Modulation of the immune system to prevent lung injury is being widely used against the new coronavirus disease (COVID-19). The primary endpoint was mortality at 7 days after tocilizumab administration. Secondary endpoints were admission to the intensive care unit, development of ARDS and respiratory insufficiency among others.
View Article and Find Full Text PDFPurpose: We aim to assess risk factors related to early readmission in previous hospitalized patients with COVID-19.
Methods: We analyzed a retrospective cohort of patients with laboratory-confirmed COVID-19 admitted to Vall d'Hebron University Hospital, Barcelona, Spain. Early readmission was defined as the need for hospitalization within a period of 60 days after discharge.
: Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) are prevalent nosocomial infections with a worrisomely increasing prevalence of multidrug-resistant causative organisms, including those with resistance to carbapenems. The addition of relebactam, a β-lactamase inhibitor, to imipenem treatment restores the antimicrobial activity against the most of multidrug-resistant Gram-negative bacteria, including some carrying β-lactamase enzyme-type carbapenemases.: The aim of this article is to summarize the current evidence regarding imipenem/relebactam for the treatment of HAP/VAP.
View Article and Find Full Text PDFWe review antibiotic and other prophylactic measures to prevent periprosthetic joint infection (PJI) after hip hemiarthroplasty (HHA) surgery in proximal femoral fractures (PFFs). In the absence of specific guidelines, those applied to these individuals are general prophylaxis guidelines. Cefazolin is the most widely used agent and is replaced by clindamycin or a glycopeptide in beta-lactam allergies.
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