Publications by authors named "Julia S Krimberg"
Article Synopsis
- Levodopa is the primary treatment for Parkinson's disease (PD) but can lead to movement problems called levodopa-induced dyskinesia (LID) with long-term use.
- This study aimed to determine the relationship between serum uric acid (UA) levels and the occurrence of LIDs in PD patients, along with how UA levels correlate with other clinical features.
- Findings revealed that lower UA levels were significantly associated with the presence of dyskinesia, and UA levels were also correlated with depressive symptoms, disease duration, and age at onset of PD.
Background: Depression is an important nonmotor symptom of Parkinson's disease (PD) and has been associated with the motor symptoms in these individuals.
Objectives: To determine whether there are relationships between depressive symptoms and abnormalities in axial postural alignment and axial motor deficits, especially postural instability, and trunk rigidity in PD.
Methods: In this cross-sectional study, 65 individuals were evaluated using the Beck Depression Inventory-II (BDI-II) for the analysis of depressive symptoms and underwent a postural assessment of head, trunk, and hip sagittal alignment through computerized photogrammetry.
Article Synopsis
- Life-space mobility (LSM) measures how people move through their daily environments, and this study focused on individuals with Parkinson disease to see how LSM relates to self-efficacy and balance.
- The study involved 88 participants and found that factors like age, disease severity, cognitive ability, and balance performance significantly impacted LSM, with 36.4% of participants classified as having restricted mobility.
- The findings suggest that enhancing balance and self-efficacy may improve community mobility for those with Parkinson disease, promoting better functional independence and overall health.
Social isolation (SI) stress results from a combination of intrinsic and environmental factors and is associated with a variety of negative developmental outcomes. Oxytocin (OXT) might play a role in the consequences of SI in the brain and periphery. We conducted a systematic review and meta-analysis to compile data about the effects of SI in the oxytocinergic system of rats and mice, and its relation to behavioral alterations.
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