A zirconocene triazenido hydride complex activates CO.

Starting from the alkyne complex CpZr(py)(η-MeSiCSiMe) (Cp = η-cyclopentadienyl, py = pyridine), the synthesis and complete characterisation of a zirconocene(IV) triazenido hydride complex and its use in the activation of small molecules is reported. The reaction with CO led to the formation of a zirconocene(IV) triazenido-formate complex, which was further investigated for its stability towards different bases with respect to the formation of formic acid. The experimentally observed reaction pathway was investigated computationally using DFT methods, revealing the favourable role of pyridine coordination in the hydrogen transfer from the triazene to the alkyne unit of the zirconocene reagent.

Synthetic strategies to bicyclic tetraphosphanes using P1, P2 and P4 building blocks.

Different reactions of Mes* substituted phosphanes (Mes* = 2,4,6-tri-tert-butylphenyl) led to the formation of the bicyclic tetraphosphane Mes*P4Mes* (5) and its unknown Lewis acid adduct 5·GaCl3. In this context, the endo-exo isomer of 5 was fully characterized for the first time. The synthesis was achieved by reactions involving "self-assembly" of the P4 scaffold from P1 building blocks (i.

Reduction of dichloro(diaza-phospha)stibanes - isolation of a donor-stabilized distibenium dication.

A reaction of antimonytrichloride SbCl3 with potassium bis(terphenylimino)phosphide K[(TerN)2P] smoothly afforded a novel class of mixed diazadipnictanes, namely dichloro(diaza-phospha)stibane [Ter2N2P((III))Sb((III))Cl2], which is considered to exist as open chain-like and cyclic isomers in an equilibrium. [Ter2N2PSbCl2] is a versatile starting material for reduction and halide abstraction experiments. Halide abstraction led to the formation of a cyclic diazastibaphosphenium cation [P(μ-NTer)2SbCl](+).

Structure and bonding of novel acyclic bisaminoarsenium cations.

The synthesis and characterization of a salt bearing a labile bisaminoarsenium cation of the type {[(Me3Si)2N]2As}(+) (9a) are described, which was obtained in the reaction of the chloroarsane [(Me3Si)2N]2AsCl (8) with GaCl3. Reacting 8 with AgOTf did not yield an arsenium salt, but the cyclo-diarsadiazane [(Me3Si)2NAs-μ-NSiMe3]2 (11) was obtained in excellent yields. Moreover, the reactivity of the analogous antimony species [(Me3Si)2N]2SbCl (12) was studied.

5-HT(1A)-receptor over-expressing mice: genotype and sex dependent responses to antidepressants in the forced swim-test.

Deficiencies in serotonergic neurotransmission are involved in the pathophysiology of depression. Due to its modulatory effect on serotonin (5-HT) release, the 5-HT(1A)-receptor is thought to play a decisive role in the therapy of this mood disorder. However, it is not fully understood how antidepressant effects are mediated by pre- and postsynaptic receptor sites.