Big infants in the neonatal intensive care unit.

Objective: This study was undertaken to identify risk factors for prolonged neonatal intensive care unit (NICU) stay in macrosomic (> or = 4000 g) neonates.

Study Design: A population-based case-control study in which 799 cases of macrosomic neonates with a prolonged NICU stay were compared with macrosomic neonates without a prolonged stay (n = 1598).

Results: Significant risk factors included: 5-minute Apgar score less than 7: odds ratio (OR) = 43.