Publications by authors named "Julia Paffile"

Positive Airway Pressure (PAP) therapy is the most common and efficacious treatment for Obstructive Sleep Apnea (OSA). However, it suffers from poor patient adherence due to discomfort and may not fully alleviate all adverse consequences of OSA. Identifying abnormal respiratory events before they have occurred may allow for improved management of PAP levels, leading to improved adherence and better patient outcomes.

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Article Synopsis
  • Memory formation involves the actin cytoskeleton's modulation at synapses, with the NCK1 protein playing a key role in this process.
  • Male mice without NCK1 show significant deficits in short-term memory and spatial learning, while female mice show specific challenges in reversal learning tasks.
  • NCK1 is crucial for stabilizing actin dynamics and dendritic spine formation in the hippocampus, highlighting its importance in understanding cognitive disorders and potential therapeutic targets.
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Background: Improving patient care and safety requires high-quality evidence. The objective of this study was to systematically review the existing evidence for patient safety (PS) and quality improvement initiatives in breast reconstruction.

Methods: A systematic review of the published plastic surgery literature was undertaken using a computerized search and following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.

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