Publications by authors named "Julia N Brown"
Article Synopsis
- ASPYRE Technology
- : ASPYRE (Allele-Specific PYrophosphorolysis REaction) was created to provide a quick, affordable, and effective genomic testing method for cancer, specifically non-small cell lung carcinoma, assessing 114 variants in 11 genes simultaneously from tumor samples.
- Testing and Results
- : When tested on various lung tissue samples, ASPYRE-Lung showed a detection sensitivity of ≤ 3% for single nucleotide variants, with perfect specificity and high analytical accuracy, matching expected results without false positives.
- Ease of Use
- : The assay requires minimal steps and standard lab equipment, with data analysis supported by a cloud-based algorithm, making it a potentially transformative tool for
Aggression is a fundamental behavior displayed universally among animal species, but hyper- or hypo-aggressiveness can be maladaptive with negative consequences for individuals and group members. While the social and ecological significance of aggression is well understood, the specific neurobiological and hormonal mechanisms responsible for mediating aggression have not been fully elucidated. Previous studies have shown a relationship between aggressive acts and circulating gonadal steroids, but whether classical nuclear steroid receptors regulate aggression in animals is still uncertain.
View Article and Find Full Text PDFBioavailability of vitamin D in malnourished adolescents with anorexia nervosa.
J Clin Endocrinol Metab
August 2011
Context: Young women with anorexia nervosa (AN) have a normal vitamin D status. The bioavailability of vitamin D during malnutrition is unknown.
Objective: The objective of the study was to examine the serum response to oral ergocalciferol in AN.
Purpose: To evaluate the dental and periodontal health of adolescents and young women with restrictive anorexia nervosa (AN), and relationship between bone mineral density (BMD) assessed by dual energy Xray absorptiometry (DXA) and dental radiographs.
Study Design: Twenty-three young women, median age 17.6 years (range 14.