Publications by authors named "Julia Moses"
Article Synopsis
- The goal of computational psychiatry is to create models that connect differences in brain function to cognitive impairments and symptoms, which are often resistant to treatment.* -
- Research shows that to predict cognitive functioning accurately, large participant samples are needed, highlighting limitations in smaller patient studies.* -
- Using a transfer learning approach on neuroimaging data from the UK Biobank, the study found that predictions of cognitive functioning improved significantly, even with smaller sample sizes, validating the effectiveness of training models on larger datasets.*
Article Synopsis
- The study aims to connect brain functioning profiles with symptoms and behaviors in psychiatric patients by introducing a new dataset.
- This dataset includes brain imaging and behavioral data from 241 individuals, with a mix of 148 people diagnosed with psychiatric illnesses and a healthy group of 93.
- It provides a comprehensive resource including high-resolution scans, fMRI data, and over 50 psychological assessments to facilitate research in neuroscience.
Background: The use of image-laden social media is hypothesized as being implicated in psychological distress in individuals with conditions affecting their appearance. However, relatively little is known about the mechanisms involved in this relationship.
Objective: This cross-sectional study examined the relationship between photo-orientated social media use and feelings of stigmatization in adults with acne, and tested whether upward skin comparisons mediate and self-compassion moderates this relationship.
A method was developed to characterize and quantify preparations of monomeric beta-amyloid (Abeta) peptide using capillary electrophoresis (CE) with UV absorbance detection. The detection limit for Abeta monomer using this method was 0.5 microM (19 pg).
View Article and Find Full Text PDFIdentification of the signal peptide-binding domain within SecA ATPase is an important goal for understanding the molecular basis of SecA preprotein recognition as well as elucidating the chemo-mechanical cycle of this nanomotor during protein translocation. In this study, Forster resonance energy transfer methodology was employed to map the location of the SecA signal peptide-binding domain using a collection of functional monocysteine SecA mutants and alkaline phosphatase signal peptides labeled with appropriate donor-acceptor fluorophores. Fluorescence anisotropy measurements yielded an equilibrium binding constant of 1.
View Article and Find Full Text PDFReducing costs and patient morbidity in the enterally fed intensive care unit patient.
JPEN J Parenter Enteral Nutr
July 2005
Background: Critically ill patients are at high risk for nosocomial infections and resultant organ dysfunction and death. These patients typically have protracted intensive care unit (ICU) courses and consume increasingly limited resources. Enteral nutrition with specific immune-modulating components has been previously shown to improve outcomes in select populations of patients, but results have been mixed in critically ill patients.
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