Publications by authors named "Julia McLane"
Arthritis Rheum
April 2004
Article Synopsis
- The study investigated the impact of subchondral bone remodeling on the progression of osteoarthritis (OA) using a rat model and the effects of alendronate (ALN), a drug that inhibits bone resorption.
- ALN treatment resulted in reduced cartilage degradation and osteophyte formation, demonstrating chondroprotective effects and suppression of bone resorption in the OA-affected joints.
- The findings suggest that targeting subchondral bone remodeling with ALN may offer a new approach to treating OA by modifying disease progression.
