Predicting ligand removal energetics in thiolate-protected nanoclusters from molecular complexes.

Thiolate-protected metal nanoclusters (TPNCs) have attracted great interest in the last few decades due to their high stability, atomically precise structure, and compelling physicochemical properties. Among their various applications, TPNCs exhibit excellent catalytic activity for numerous reactions; however, recent work revealed that these systems must undergo partial ligand removal in order to generate active sites. Despite the importance of ligand removal in both catalysis and stability of TPNCs, the role of ligands and metal type in the process is not well understood.

Temporomandibular joint total replacement using the Zimmer Biomet Microfixation patient-matched prosthesis results in reduced pain and improved function.

Objective: The aim of this study was to evaluate pain and maximum interincisal opening (MIO) in patients treated with the Zimmer Biomet Microfixation patient-matched alloplastic temporomandibular joint (TMJ) prosthesis.

Study Design: We performed a retrospective cohort study of patients who had undergone bilateral or unilateral TMJ total joint replacement (TJR). The primary outcome variables were pain and MIO, which were measured at various time points between 12 and greater than 60 months.

Gender Differences and Predictors of Work Hours in a Sample of Ontario Dentists.

Purpose: To determine the influence of gender on weekly work hours of Ontario dentists.

Methods: In 2012, a 52-item survey was sent to a random sample of 3000 Ontario dentists (1500 men and 1500 women) to collect information on personal, professional and sociodemographic characteristics. The resulting data were analyzed using descriptive statistics and linear regression modeling.

Gender Differences and Predictors of Practice Ownership in a Sample of Ontario Dentists.

Purpose: To examine the influence of gender on practice ownership among Ontario dentists.

Methods: In 2012, a 52-item survey was sent to a random sample of 3000 Ontario dentists (1500 men and 1500 women) to collect information on personal, professional and sociodemographic characteristics. The resulting data were analyzed using descriptive statistics and linear regression modeling.

The feminization of dentistry: implications for the profession.

Over the last 40 years, the proportion of women in dentistry has been rising steadily, raising questions about the effects of this feminization on the profession. A review of the literature, although limited, highlights potentially important areas related to gender, including impact on work hours, practice models, professional incomes, the dentist-patient relationship, clinical philosophies, specialty practice, academia and leadership. Although cohorts of predominantly female dentists are only beginning to enter the workforce and, thus, it is difficult to predict the long-term effects, some trends are evident: women are less likely than men to own their practice; women may work 4-6 fewer hours a week and see fewer patients; there is a pay differential; female general practitioners and specialists appear more likely to work in urban centres; and women are less prominent in the specialties, academia and leadership roles.

Adolescent bipolar disorder: a clinical vignette.

Adolescence is a vulnerable developmental phase marked by physical, psychological, and social changes that rapidly expose young people to a wide range of new stressors. When differentiating between bipolar disorder and teenage "acting out," a careful history is important. Adolescent bipolar disorder is a psychiatric illness characterized by fluctuating episodes of mood elevation and depression that is frequently neither recognized nor formally diagnosed.

Extremely low frequency pulsed electromagnetic field designed for antinociception does not affect microvascular responsiveness to the vasodilator acetylcholine.

A 225 microT, extremely low frequency, pulsed electromagnetic field (PEMF) that was designed for the induction of antinociception, was tested for its effectiveness to influence blood flow within the skeletal microvasculature of a male Sprague-Dawley rat model (n = 103). Acetylcholine (0.1, 1.

Light alters nociceptive effects of magnetic field shielding in mice: intensity and wavelength considerations.

Previous experiments with mice have shown that repeated 1 hour daily exposure to an ambient magnetic field-shielded environment induces analgesia (antinociception). The exposures were carried out in the dark (less than 2.0x1016 photonss-1m-2) during the mid-light phase of the diurnal cycle.

A randomized, double-blind, placebo-controlled clinical trial using a low-frequency magnetic field in the treatment of musculoskeletal chronic pain.

Exposure to a specific pulsed electromagnetic field (PEMF) has been shown to produce analgesic (antinociceptive) effects in many organisms. In a randomized, double-blind, sham-controlled clinical trial, patients with either chronic generalized pain from fibromyalgia (FM) or chronic localized musculoskeletal or inflammatory pain were exposed to a PEMF (400 microT) through a portable device fitted to their head during twice-daily 40 min treatments over seven days. The effect of this PEMF on pain reduction was recorded using a visual analogue scale.

A literature review: the effects of magnetic field exposure on blood flow and blood vessels in the microvasculature.

The effect of magnetic field (MF) exposure on microcirculation and microvasculature is not clear or widely explored. In the limited body of data that exists, there are contradictions as to the effects of MFs on blood perfusion and pressure. Approximately half of the cited studies indicate a vasodilatory effect of MFs; the remaining half indicate that MFs could trigger either vasodilation or vasoconstriction depending on initial vessel tone.

Exposure to a specific pulsed low-frequency magnetic field: a double-blind placebo-controlled study of effects on pain ratings in rheumatoid arthritis and fibromyalgia patients.

Background: Specific pulsed electromagnetic fields (PEMFs) have been shown to induce analgesia (antinociception) in snails, rodents and healthy human volunteers.

Objective: The effect of specific PEMF exposure on pain and anxiety ratings was investigated in two patient populations.

Design: A double-blind, randomized, placebo-controlled parallel design was used.

Childhood bipolar disorder: a clinical vignette.

Bipolar disorder in children and adolescents can easily be misdiagnosed, as symptom patterns overlap with other mood disorders and attention-deficit/hyperactivity disorder and commonly differ from adult presentations. A detailed description of the child's behavioral history and previous treatment response is critical to accurate diagnosis. Although studies with children are limited, a number of psychopharmaceuticals have been shown to provide therapeutic benefit.