LACTATE CAN BE A MARKER OF METABOLIC SYNDROME IN SEVERE OBESITY?

Background: In the last decades, numerous studies have confirmed the importance of lactate - by-product to the nutrient signal of the intracellular redox state - to regulatory functions in energy metabolism.

Aim: To evaluate changes in blood lactate in patients with severe obesity and its correlation with body composition and metabolic profile.

Methods: Twenty-four people with severe obesity (BMI=40 kg/m2) were evaluated in a prospective case-control study before and six months after Roux-in-Y gastric bypass.

Magnesium status and the physical performance of volleyball players: effects of magnesium supplementation.

The aim of this study was to test the hypothesis that magnesium supplementation influences the physical performance of volleyball players, as the efficacy of this approach remains questionable. Twenty-five professional male volleyball players were assigned randomly to experimental (350 mg Mg · d(-1), 4 weeks) and control groups (500 mg maltodextrin · d(-1), 4 weeks) maintaining inter-group homogeneity of urinary magnesium. Erythrocyte, plasma and urinary magnesium levels, plasma creatine kinase activity, lactate production, maximal oxygen uptake (VO2 max) and plyometric (squat jump, countermovement jump, countermovement jump with arm swing) and isokinetic (peak torque, potency and total work) performances were evaluated before (T0) and after (T1) supplementation.

Cardiovascular responses during isokinetic muscle assessment in claudicant patients.

Background: Isokinetic dynamometry is becoming increasingly important for the assessment of muscle function in individuals with intermittent claudication. However, there is still little information available about the cardiovascular responses of these patients during this type of assessment.

Objective: To assess and compare the cardiovascular responses recorded during the assessment of muscle strength and endurance for two exercises commonly used in patients with IC (plantar flexion/dorsiflexion and knee flexion/extension).

Use of intrathecal morphine infusion for spasticity.

Objective: To study the efficacy of intrathecal morphine infusion to treat spasticity.

Setting: Functional Neurosurgery Division of University of São Paulo, Brazil.

Method: Twelve patients with clinical refractory spasticity were studied.