Publications by authors named "Julia M Beatrice"
Article Synopsis
- Blood count abnormalities are common in young COVID-19 patients, with atypical lymphocytes and eosinopenia being the main changes observed in those evaluated in emergency rooms.
- In a study of 93 children aged 0 to 10, the presence of underlying health issues significantly increased the likelihood of hospitalization, and higher neutrophil to lymphocyte ratios (NLR) were associated with severity.
- Eosinopenia emerged as a notable predictor of disease severity in hospitalized children, suggesting that specific CBC changes can provide insights into clinical outcomes for pediatric COVID-19 cases.
Background: Kidney transplantation is the gold standard treatment for children with end-stage chronic kidney disease. Graft thrombosis is an important cause of graft failure, with high morbidity, mortality, and impact on quality of life and to the health system. The role of thromboprophylaxis in this setting is still uncertain.
View Article and Find Full Text PDFAutoantibodies are biomarkers for autoimmune disease diagnosis, monitoring, and prediction. Therefore, this study established the frequency of latent and overt polyautoimmunity in children and adolescents with >6 months of diagnosis of immune thrombocytopenia (ITP). Forty-seven patients with chronic or persistent disease had non-organ-specific and organ-specific autoantibodies assessed.
View Article and Find Full Text PDFEssential thrombocythemia is an acquired myeloproliferative disorder characterized by the proliferation of megakaryocytes in bone marrow, leading to a persistent increase in the number of circulating platelets and thus increasing the risk for thrombotic and hemorrhagic events. The disease features leukocytosis, splenomegaly, vascular occlusive events, hemorrhages and vasomotor disorders. The intricate mechanisms underlying the molecular pathogenesis of this disorder are not completely understood and are still a matter of discussion.
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