Does location matter? Characterisation of the anatomic locations, molecular profiles, and clinical features of gliomas.

Background: Neuroanatomic locations of gliomas may influence clinical presentations, molecular profiles, and patients' prognoses.

Methods: We investigated our institutional cancer registry to include patients with glioma over a 10-year period. Statistical tests were used to compare demographic, genetic, and clinical characteristics among patients with gliomas in different locations.

Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients.

Background: Sex is recognized as a significant determinant of outcome among glioblastoma patients, but the relative prognostic importance of glioblastoma features has not been thoroughly explored for sex differences.

Methods: Combining multi-modal MR images, biomathematical models, and patient clinical information, this investigation assesses which pretreatment variables have a sex-specific impact on the survival of glioblastoma patients (299 males and 195 females).

Results: Among males, tumor (T1Gd) radius was a predictor of overall survival (HR = 1.